Western Cartridge Co. had a load for the .38 S&W called the .38 Super Police which used a 200 gr. Lubaloy bullet. It was safe to fire in any Colt, S&W or other medium frame revolver. It doesn't matter what the powder charge is as long as the chamber pressures are kept within the limits of the standard .38 S&W load. The K frame S&W is absolutely safe to fire with with the 200 grain S&W cartridge.