Appearantly it does better with heavy bullets in 308. Seems I remember reading a magazine article 14-15 years ago that stated Alliant had won the contract to furnish powder for loading 7.62mm M118LR sniper ammo and RE 15 was selected.
I do know it's a very good choice for heavy 5.56mm loads. 24.0grs under a Hornady 75gr bthp is a really accurate load and so is 24.9grs under a 77gr smk, which duplicates the Mk 262 mod 0/mod 1 round.