If you have to much air space your going to have to use a filler to keep the powder against the primer, I suffered over pressure in my 6.5x284 trying low density loads for less pressure high velocity (Using a faster powder) had a primer fall out after firing 2 rounds so stopped. I surmised that with the increased air space suffering more of a detonation as the flash ran across the top of the powder I now ensure load density is at 90-95%.
The load I was trying to develop was with WIN 760 ball powder and going from my Quickload program with the powder variation set at 5% it showed good pressure from memory around the 48-49000 psi for about 2850-2900fps with a 140gn VLD using a 215M primer as the load density was around the 70-75% I think, out of a 30" barrel so I did not just say in my head this equals that and alls well in the world.
It is never really a good idea to go below minimum loads even with years of experience and constructing the load in your head by saying this equals that..... as manuals state going under minimum load data it can be a dangerous undertaking.
Slug the bore and see what it mikes to V's your cast measurement I do not see the extra 5 grains of weight as a factor to drop below the recommended lowest load