Explosion at Lake City...

[CINDERS]

Nothing comes close to this one though as far as a non-nuclear explosions go ~ https://www.google.com.au/url?sa=t&r...VqhTvH6Hl4kd6w
https://www.google.com.au/url?sa=t&r...wORIaQ2qL1kkAQ

Some idea of the scale ~ At 9:04:35 am, the out-of-control fire aboard Mont-Blanc finally set off her highly explosive cargo.[53] The ship was completely blown apart and a powerful blast wave radiated away from the explosion at more than 1,000 metres (3,300 ft) per second. Temperatures of 5,000 °C (9,030 °F) and pressures of thousands of atmospheres accompanied the moment of detonation at the centre of the explosion.[54][23] White-hot shards of iron fell down upon Halifax and Dartmouth.[55] Mont-Blanc's forward 90 mm gun, its barrel melted away, landed approximately 5.6 kilometres (3.5 mi) north of the explosion site near Albro Lake in Dartmouth, while the shank of her anchor, weighing half a ton, landed 3.2 kilometres (2.0 mi) south at Armdale.[56]

Death toll and injured ~ Over 1,600 people were killed instantly and 9,000 were injured, more than 300 of whom later died.[23] Every building within a 2.6-kilometre (1.6 mi) radius, over 12,000 in total, was destroyed or badly damaged

Thing is both in fact all the ones in this thread are pretty damn awful, put the clock back to those early years where treatment of patients were woefully inadequate for the numbers that were to flood the hospitals and transport system well what was left of the system.