Experience with early modern replicas, made before the proper screw and thread pitch of the breechblock were rediscovered, seemed to indicate that while reloading was rapid, it seemed to be necessary to first lubricate the breech screw (originally with a mixture of beeswax and tallow) or else the (replica) rifle would foul so much that it needed cleaning after three or four shots. However, through the research efforts of DeWitt Bailey and others, the properly made reproduction Ferguson rifle, made according to Patrick Ferguson's specifications of the 1770s, can fire beyond sixty shots.
According to Forgotten weapons vid that I just looked at they used a .65 caliber ball first off for the most accurate shooting.
Then after the rifle was fouled (How many shots did not say) change to a .61 caliber ball the load they used in the video was 75gns of 3F Swiss(No liability accepted in the use of this load only repeating what was on the video)