One of my first LE's was an MLE in 410 shotgun calibre.
Great little rabbiting rifle, once the chamber was properly reamed out,
You can use the existing bolt, bolt head and extractor Simply 'smooth bore' the barrel and ream the chamber.
A 410 only has a chamber pressure of ~12000 psi. SAAMI state that a .22LR has a chamber pressure of ~ 24,000psi
308 is ~ 62,000 psi
303 is ~ 50,000 psi